Amfar Research Grant

Request for Proposals

Targeted Biomedical Research: Exploring the mechanisms for HIV persistence and the potential for HIV eradication

Please see the complete RFP:


Letter of Intent due no later than Wednesday, October 15, 2014

Maximum funding: $180,000, including maximum 20% indirect costs.
Please note that the performance period is for two years starting February 1, 2015.

Forms & Instructions

Submission of a research Letter of Intent (LOI) is now an online process. Take the following steps to request web portal log-in credentials and Letter of Intent (LOI) forms and instructions:

CLICK HERE to download the request form.

Complete the form and email it to It is strongly suggested that all requests for log-in credentials and LOI materials are made, at the very latest, by 12:00 PM EST on October 10, 2014. Please note that amfAR’s offices will be closed in observance of Columbus Day on October 13, 2014.

Log-in credentials are not interchangeable. A separate request form must be sent for each potential applicant.

If you cannot send the request form, please email the following information to to request web-portal log-in credentials and forms. Please be sure to include all of the information below, otherwise credentials and forms cannot be provided:

Principal Investigator name (first and last), degree(s), and email address
Applying Institution name, city, state, and country
Project title (maximum 80 characters and spaces)
One sentence description of the research you are proposing.
Five to ten keywords relevant to the research you are proposing.
The names and institutions of at least two scientists who have expertise relevant to the research you are proposing.

This RFP solicits proposals relevant to exploring the mechanisms for HIV persistence and the potential for HIV eradication. Highly active antiretroviral therapy (HAART) has significantly impacted the health of individuals infected with HIV-1. However, if therapy is interrupted, there is a rapid resumption of viral replication. Understanding the mechanisms by which the virus is able to persist in the face of therapy is necessary in order to identify strategies that may interrupt viral persistence and ultimately lead to viral eradication. amfAR wishes to support basic, pre-clinical, clinical, and especially translational research exploring the mechanisms whereby HIV infection persist; the chronic nature of viral reservoirs and latency; and barriers to the eradication of HIV, with the potential goal of ultimately eliminating HIV infection.

amfAR grants are made to nonprofit organizations worldwide. Principal investigators must hold a doctoral degree and be affiliated with a nonprofit research institution. Applicant investigators need not be U.S. citizens, and there are no restrictions as to age, color, creed, gender, medical condition, handicap, national origin, parental status, political affiliation, race, religion, marital status, or sexual orientation.

See the RFP posted at for details about specific areas of interest, submission requirements and additional information.

If you have difficulty accessing the RFP or downloading the forms please contact

Please forward this e-mail to colleagues who might also be interested in the program or in responding to future amfAR RFPs.

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